PSA Oxygen Plants For Biopharmaceutical

High purity requirements: In the biopharmaceutical process, especially in cell culture and fermentation, high-purity oxygen is required to promote cell growth and metabolism. High-purity oxygen helps improve production efficiency and product consistency.
No pollutants: Oxygen cannot contain impurities that are harmful to the biopharmaceutical process, such as nitrogen, carbon dioxide, water vapor and other possible contaminants. These impurities may affect the environment in which cells grow, and even cause cell death or product quality degradation.
Stability: The purity and supply of oxygen must remain stable. Any fluctuations may cause parameter changes in the biopharmaceutical process, affecting the quality and safety of the final product.
Sterility requirements: In some biopharmaceutical processes, such as the production of sterile drugs, oxygen needs to reach a sterile level to prevent microbial contamination.
Compliance with regulatory standards: The purity and quality of oxygen used in biopharmaceuticals must comply with relevant pharmaceutical production quality management specifications (GMP) and other regulatory requirements.

The purity of oxygen used in biopharmaceuticals is required to be above 90%, and sometimes even above 99%. High-purity oxygen helps improve the efficacy and safety of drugs and is an integral part of biopharmaceutical processes.

What is the operating process of PSA oxygen generator?

Adsorption stage: Under pressurized conditions, air passes through an adsorption tower equipped with molecular sieves. Molecular sieves have a higher adsorption capacity for impurities such as nitrogen, carbon dioxide and water, while oxygen passes through the adsorption tower to achieve the initial separation of air.
Equalizing pressure stage: When the adsorption capacity of the molecular sieve in the adsorption tower reaches saturation, the adsorption tower enters the equalizing pressure stage. This stage prepares for the next stage by reducing the pressure in the tower while maintaining the output of oxygen.
Desorption stage (countercurrent purge): After the pressure of the adsorption tower is reduced, part of the product oxygen is used as a purge gas and flows through the adsorption tower in the reverse direction. This process helps the molecular sieve release the adsorbed nitrogen and other impurities to achieve the regeneration of the molecular sieve.
Equalizing pressure drop stage: After the desorption stage, the adsorption tower is further depressurized to prepare for the next adsorption cycle.
Regeneration stage: Through the above steps, the molecular sieve is regenerated and ready to re-enter the adsorption stage.